Carcicoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis

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Serum Carbohydrate Antigen 19-9 as an Indicator of Liver Metastasis of Colorectal Carcinoma

Colorectal cancer (CRC) is one of the most common malignancies in the world, which leads to the third highest tumor-related mortality (Gillams and Lees, 2009; Van Tilborg et al., 2011). Liver is the most common organ that CRC metastasize to and liver metastasis (LM) can be detected in about 25% patients at initial diagnosis of CRC (Min et al., 2002). What’s more, about 50% of CRC patients final...

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Association between carcinoembryonic antigen, carbohydrate antigen 19-9 and body mass index in colorectal cancer patients

Carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) have been well recognized as tumor markers for colorectal cancer. Previous studies suggested that obesity is inversely associated with the screening of CEA and CA19-9 levels and may reduce screening sensitivity. This study was conducted to evaluate the association of body mass index (BMI) with serum CEA and CA19-9 concentrati...

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Prognostic relevance of carbohydrate antigen 19-9 levels in patients with advanced biliary tract cancer.

Serum carbohydrate antigen 19-9 (CA 19-9) has been identified as biochemical marker for biliary tract cancer (BTC). The purpose of this study was to evaluate its value as a treatment response marker and its value as a prognostic parameter in patients with unresectable BTC. We analyzed 70 patients with BTC treated with chemotherapy. CA 19-9 levels before and after two treatment courses were anal...

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Prognostic value of pretreatment serum carbohydrate antigen 19-9 level in patients with colorectal cancer: A meta-analysis

BACKGROUND Carbohydrate antigen 19-9 (CA 19-9) is one of the most frequently used tumor markers for gastrointestinal cancer, particularly for diagnostic purposes. However, its value in predicting prognosis remains controversial. In this study, we sought to clarify this by conducting a meta-analysis of relevant studies. METHODS We systematically searched several databases, including PubMed, EM...

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Clinicopathologic and Prognostic Value of Serum Carbohydrate Antigen 19-9 in Gastric Cancer: A Meta-Analysis

BACKGROUND The clinical value of carbohydrate antigen (CA) 19-9 in gastric cancer is controversial. We evaluated the clinicopathologic and prognostic value of CA 19-9 in gastric cancer. METHODS A literature search was conducted in PubMed and Embase databases. Odds ratios (ORs), risk ratios (RR), hazard ratios (HRs), and 95% confidence intervals (CIs) were used as effect measures. RESULTS Th...

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ژورنال

عنوان ژورنال: Oncology Letters

سال: 2012

ISSN: 1792-1074,1792-1082

DOI: 10.3892/ol.2012.574